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$39,000
Build your dream home in the City of Seneca! This .27-acre residential lot is ready for new construction and offers an excellent opportunity for a custom build or investment. The property has already been graded for a new home, and a graded access road from the street to the lot has been established, as shown on the recorded plat (see supplements). The lot includes both water and sewer taps, helping streamline the building process. Conveniently located within city limits, this property provides easy access to local shopping, dining, and amenities while still offering a comfortable residential setting. Sellers are licensed South Carolina real estate agents.

534 E South 5th Street, Seneca
$39,000
Build your dream home in the City of Seneca! This .34-acre residential lot is ready for new construction and offers an excellent opportunity for a custom build or investment. The property has already been graded for a new home, and a graded access road from the street to the lot has been established, as shown on the recorded plat (see supplements). The lot includes both water and sewer taps, helping streamline the building process. Conveniently located within city limits, this property provides easy access to local shopping, dining, and amenities while still offering a comfortable residential setting. Sellers are licensed South Carolina real estate agents.

530 E South 5th Street, Seneca
$325,000
Suite B has a1254 SF floor plan with an open floor plan, an office, kitchenette, bathroom, storage area. Enough space to convert to 5 additional offices. Property can also be used by the new owner for Retail space. Suite B is located in one of the best spots in Seneca with heavy traffic passing by on By Pass 123. Close to shopping, dining, medical, downtown Seneca, Lake Keowee Marina, Close to Everything ! Buyers to verify everything of importance including square footage. Owner financing terms available.

528 By Pass 123 Highway Unit Suite B, Seneca
$30,000
LIVE WHERE YOU PLAY! Build your dream home on this beautiful wooded lot in the gated Cross Creek Golf Community. Cross Creek is built around an 18-hole Dye-designed golf course. Amenities include a Clubhouse with restaurant, Pro Shop, Community Pool, Pickelball Courts and boasts an active social community.

Lot 11 Dog Leg Lane, Seneca
$1,695,000
Great Opportunity to own an all brick/concrete building in the City of Seneca SC. Located on an busy road in a growing area of Western Upstate SC. The Building Already has 2 tenants in place who now occupy close to 8000 Sqft which leaves over 7000 sqft for another tenant or an owner occupy situation. The building is built like a warehouse with 16-foot ceilings and No-load bearing walls. Lots of options to bring in other tenants or self-occupy.

518 W North 1st Street, Seneca
$395,000
Don't miss this exceptional opportunity to own a +/-0.99-acre flat, graded commercial lot ideally located just off Wells Highway. With excellent visibility and easy access, this versatile property is perfectly positioned in a high-demand area, less than two miles from Prisma Hospital. Whether you're looking to develop office space, retail, medical facilities, or other commercial ventures, this lot offers the ideal foundation. The property’s level terrain and grading significantly reduce development costs, allowing for a smoother and faster build process. The property is also being offered as a ground lease and as a build to suit opportunity. Contact agent for lease terms.

Corner of Wells Hwy. & Return Church Rd. Highway, Seneca
$385,990
3 Beds ⋅ 2 Baths
Proposed Construction Opportunity! Customize the home by visiting the design center to pick colors and options. Price listed is before options are added. Welcome to Wells Crossing! Clemson's closest new home community offering private single and two-story living near lake Keowee The Cooper 3 floor plan is a versatile, ranch-style home offering comfortable living spaces with flexible design options. As you enter into your spacious entry hall, you have 2 bedrooms and a full bath adjacent to the foyer. You could also have a dedicated office space or formal dining room in lieu of one of the bedrooms. The kitchen is a chefs dream with beautiful cabinetry in the color of your choice, Quartz or granite countertops, center island with sink for extra prep space and additional seating, stainless steel gas appliances and options such as tiled backsplash and under cabinet lighting. The large living room is perfect for entertaining and features high ceilings, tall windows for lots of natural light and an optional gas fireplace. Off the breakfast room is the outdoor patio which you could transform into a covered porch or screened in porch. The Primary Suite is situated off the living room and features double vanities, generous walk in closet and step in shower or you can upgrade to a tiled shower or Roman shower with double showerheads. Upstairs you can have an additional bedroom and full bath, large multi use room or both. Smart home technology, energy-efficient construction, and a dedicated local warranty teamensure lasting convenience and comfort. Wells Crossing is perfectly situated for those seeking a vibrant lifestyle with easy access to everything they need. The community boasts 2 pickleball courts, open greenspace, sidewalks, and street lights in a beautiful setting. Minutes from top ranked Clemson University, Lake Hartwell, Lake Keowee, and 45 minutes to Downtown Greenville. Situated just off Hwy. 123 and right outside the city limits of Clemson . Craving a taste of history and local charm? Downtown Seneca is within a 10-minute drive away, offering a variety of shops, restaurants, and entertainment options. For outdoor enthusiasts, the breathtaking beauty of Lake Keowee awaits, with endless opportunities for recreation and relaxation – all within a 10-minute reach. Wells Crossing is a desirable community in a prime location. Come by today for more information and make Wells Crossing your new home.

457 Fox Pond Drive, Seneca
$250,000
3 Beds ⋅ 2 Baths
Make a splash this summer at 101 Pleasant Drive! This charming 3-bedroom brick home sits proudly on a corner lot just moments from Seneca’s historic Ram Cat Alley. Enjoy the perfect blend of in-town living and outdoor fun with your own private in-ground pool and inviting backyard retreat. Classic curb appeal, a prime location, and the comfort of home—all waiting for you in the heart of Seneca!

101 Pleasant Drive, Seneca
$24,500
OWNER FINANCING OFFERED BY SELLER! Nice level lot located near the end of a quiet cul-de-sac in the established Brookwood Subdivision of Seneca. The property sits on a nicely paved road and has a small creek along the edge, adding a touch of natural charm. Sewer, natural gas, and electricity are available, making it a convenient site for a new home. It would also make an excellent option for a builder looking for a spec home lot, with utilities in place and an easy-to-build layout. Located near downtown Seneca, this property offers quick access to grocery stores, the hospital, schools, and Lake Keowee while still maintaining a peaceful neighborhood setting.

305 CREEK Drive, Seneca
$799,000
BEST LOCATION IN DOWN TOWN SENECA ! Prime Downtown Seneca Commercial Opportunity – 124 & 118 N Townsville St OPPORTUNITY ZONE ! This exceptional dual-property, two store-fronts commercial building in the heart of downtown Seneca, SC offers high visibility 11,500 VPD and unparalleled foot traffic. The Ye Old Sandwich Shoppe Restaurant (124 N Townsville) has 3224 SF and the Ice Cream/Confections Shoppe with large banquet room for celebrations (118 N Townsville) has 2548 SF. Both spaces present a unique opportunity for an established business or investor. These buildings feature 5772 SF, Hydro-Top Roof, Solar Hot Water With Electric Backup, Three HVAC'S. Situated in a vibrant downtown location, this property is perfectly positioned to capitalize on the city’s exciting developments: the new 702-Seat Performance Arts Center being constructed a few feet away directly beside the buildings estimated opening December 2026 and a 2000 seat State-Of-The-Art amphitheater just one block away opened June 19th, 2026. These upcoming venues are expected to draw significant traffic, making this location a prime hotspot for dining, retail, and entertainment businesses. Enjoy the Jazz Fest with live entertainment every Thursday evening during the Spring, Summer, Fall featuring a block party with street dancing and out door dining ! Don’t miss your chance to own a highly visible, strategically located property in a growing downtown area with strong economic and cultural activity. Buildings can be offered separately. Ye Ole Sandwich Shoppe Restaurant 3224 SF at 124 N. Townville Street and the Ice Cream Store 2548 SF at 118 N. Townville Street. Owner financing terms available. Owner retired, both buildings are vacant.

124 and 118 N Townville Street Unit Ye Ole Restaurant, Seneca
$429,943
Prime Downtown Seneca Commercial Opportunity 110 E N 1st Street | Seneca, SC Position your business for success in the heart of thriving downtown Seneca. This versatile commercial property offers 5,000 sq ft total — with 2,500 sq ft on the main level and an additional 2,500 sq ft upstairs — providing ample room for retail, office, dining, or mixed-use concepts. Enjoy unbeatable walkability with steady foot traffic, nearby shops, restaurants, and community events right outside your door. The prominent street-front location ensures high visibility and easy access for customers. Whether you’re an investor seeking rental potential or an entrepreneur ready to bring your vision to life, this property offers the space, location, and flexibility to make it happen. KEY FEATURES: Approx 5,000 sq ft total (2,500 sq ft per floor) Prime downtown Seneca address High-visibility storefront Walkable to dining, shopping, and events Endless potential for retail, office, or mixed-use This is your chance to own a cornerstone property in one of the Upstate’s most exciting downtown districts.

110 E N 1st Street, Seneca
$319,500
3 Beds ⋅ 3 Baths
Welcome to Fairfield Place, a Great Southern Homes community boasting larger floorplans with many upgrades for the money. 1044 Fairfield Dr is full of upgrades over the standard floorplan to include a stainless appliance package, natural gas stove, gas fireplace, blind package, screened patio, washer/dryer that stays and integrated technology package. Multi zoned central heat/air. This 3 bedroom, 3 full bath home also offers a large flex space upstairs with plenty of storage. A 3 zone irrigation system helps to keep the yard looking nice along with low maintenance landscaping. Natural gas appliances to include the central heat, water heater and fireplace. Centrally located near downtown Seneca it’s only minutes to Ram Cat Alley for some "Jazz on the Alley" or local car shows along with plenty of dining options. Home is now vacant and ready for immediate occupancy! Seller is offering $5000 towards closing with acceptable offer!

1044 Fairfield Drive, Seneca
$289,000
3 Beds ⋅ 2 Baths
Welcome to this beautifully designed new construction home by Gus Suarez Construction, located on a desirable corner lot in the heart of historic downtown Seneca, SC. Just minutes from Ram Cat Alley, Clemson University, Lake Keowee, and all the charm and convenience of Oconee County, this three bedroom, two full bath home offers an open floor plan perfect for modern living. The great room features vaulted ceilings that enhance the spacious feel, flowing seamlessly into a well-appointed kitchen with granite countertops, a dedicated pantry, and adjacent laundry area. The master suite is conveniently located on the main level and boasts a large walk-in shower. Two additional guest bedrooms and a full bath provide plenty of room for family or visitors. A one-car attached garage and rear patio add function and comfort. Estimated completion is approximately 90 days, with current framing nearing completion. A one-year builder’s warranty is included for peace of mind. Photos are of a similar home previously built by the same builder. Don’t miss your opportunity to own new construction in one of Seneca’s most walkable and vibrant locations.

403 E South 4th Street, Seneca
$794,900
5 Beds ⋅ 4 Baths
The Aberdeen One of our newest plans being offered in the beautiful Cross Creek Golf Course Neighborhood - This is a "To be built home". Look out the back of the home to a fairway and up a hill to the green - beautiful view, the back of the lot adjoins the golf course. Just 2 miles from shopping, restaurants, grocery stores, hospital and only 10 minutes to both LAKE KEOWEE and LAKEHARTWELL. Cross Creek is a hidden gem surrounded by a beautiful 18-hole Pete Dye course. Cross Creek has a Bar Restaurant in the Club House and an event room that can be used for any special event you would be planning. Enjoy dinner at the restaurant and a dip in the community pool. Walk up to your large porch and enter into an open floor plan with Vaulted ceilings in the Great Room. A great entertaining space with fireplace in the Great Room which opens to a large Kitchen with a large island that opens to The Dining area and Great Room. The master suite which includes a huge walk in closet, private toilet area, wonderful ceramic tile shower and soaking tub. The garage entry has a nice mudroom with a powder bathroom, Laundry and Pantry leading into the great Kitchen area. This beautiful walkout lot provides a great lower level with 3 bedrooms / Office and 2 full bathrooms and a huge Rec Room. Wait, this home also has an oversized *2* stall garage and a stunning exterior that will be painted Hardi board. Hunter Quinn Homes is able to build on your lot and on lots we own. We can help you find that perfect lot to build your new home. We build across all the Upstate, call Glenn to discuss this exciting opportunity. You have time to customize this home and make changes. Confirm all finishes and colors with Builder. Please see crosscreekplantation.com for membership fees and additional info.

2610 Dog Leg Lane, Seneca
$2,100,000
Total 4.67 acres with 2.74 Acres at 99 Northampton Road zoned Highway Commercial over looking US By Pass 123. The paved parking lot has 3 entrances. A 1500 SF brick building viewing By Pass 123 traffic is ideal for advertising signage facing the traffic. Environmental Phase 1 completed for a clean site.The property was most recently occupied by Builders Source for their lumber-building materials prior to building a new store. The former developer/owner designed a site plan with 4 Hilltop office buildings. The adjoining 1.93 acres is located off Hill Top Drive. If a smaller parcel lot is needed, acreage also offered at $ 500,000 per acre and higher based on lot lines and parcel size. Perfect spot for a retail new tire store, restaurant, and much more ! Buyers to verify everything of importance. Close to Lake Keowee, downtown, shopping, dining, medical, Clemson, close to everything !

99 Northampton Road Unit w/Hill Top Drive acreage, Seneca
$3,500,000
4.3 acres located at 1018 E. North 1st Street, across from the QT-Quik Trip and the Hampton Inn, with visibility from US By Pass Highway 123, the acreage is next to the Shine On Seneca Car Wash with high traffic volune from By Pass 123. The entire acreage is listed at $ 3.5M. Also available at $ 750,000 per acre and higher based on lot lines and parcel size. The acreage is level with two curb cuts for access from E. North 1st Street and also has access from West Clemson Street to US By Pass 123. Environmental Phase 1 completed for a clean site. Perfect spot for a retail new tire store, restaurant, extended stay hotel, great location for everything leading to the Gate Way of Down Town Seneca. Buyers to verify everything of importance. Located within the City Limits of Seneca, walking distance to Ingles, CVS, Publix, close to shopping, dining, medical, Lake Keowee Marina, minutes from Clemson University.

1018 E. North 1st Street, Seneca
$325,000
Corner level lot with shade trees at E. North 1st Street 1.29 acres located at the Gate Way to down town City of Seneca. 196 ft of road frontage, all utilities on site. Phase 1 Environmental completed by Goldie and Associates for a clean site. Close to town, shopping, dining, Ram Cat Alley. Minutes from Lake Keowee and Clemson University ! Buyer to verify everything of importance !

911 E. North 1st Street Street, Seneca
$93,500
Relax and enjoy a swim or tennis match at the Stillwater Recreation Complex. Talk a walk through Stillwater's 28 acres of preserved woodland-bordered by protected Clemson University property-and experience wildlife in its natural habitat. The Stillwater is convenient to Clemson and Seneca. Ask about our builder program on a lot of your choice.

00 Stillwater Drive, Seneca
$999,949
15,600 SF+/- historical 3 level brick free standing corner building one block from Ram Cat Alley. The owner's Young Fashions retail currently occupies the main level. Buyers to verify everything of importance including square footage. Opportunity Zone. Advance notice required to show !

235 Main Street, Seneca
$9,500
1/2 acre lot in downtown Seneca. Subject to zoning, R-6 One-family residential district purposes. Manufactured housing not allowed. Within Seneca city limits.

E North 3rd Street Unit Corner of Walnut St., Seneca
$3,833,000
76.66 acres with in the city limits of Seneca with all utilities available. The 31.66 acres that fronts the Frontage Road and Blue Ridge Blvd is Tax Map Number 520-80-01-002. Tax Map Number 520-80-01-001 45+/- acres is being surveyed for exact acreage located off of Knollwood Drive. New owner can apply for zoning with the city of Seneca for single family, multi-family, mixed commercial, commercial, etc., this Crescent land has never been zoned. The Lake Keowee interior acreage is close to town, shopping, dining, medical, Clemson University. Buyers to verify everything of importance.

76.66 acres Frontage Road and Knollwood Drive Road Unit Keowee Interior, Seneca
$1,734,700
31.54 acres with all utilities available with in the City Limits of Seneca. The Lake Keowee interior acreage fronts Blue Ridge Blvd and Frontage Road. New owner can apply for zoning with the city of Seneca for single family, multi-family, mixed commercial, commercial, etc., this Crescent land has never been zoned. Walking distance to the Prisma Hospital. Close to shopping, dining, medical, Lake Keowee, Clemson University, close to everything ! Buyers to verify everything of importance.

31.54 acres Frontage Road Unit 31.66 acres Keowee, Seneca
$2,250,000
45+/- acres Lake Keowee interior acreage with in the city limits of Seneca with all utilities available. A new survey has been ordered for exact acreage. New owner can apply for single family, multi-family, mixed commercial, commercial, etc. zoning with the city of Seneca, this Crescent land has never been zoned. Close to town, shopping, dining, medical, Clemson University. Buyers to verify everything of importance.

45+/- acres Knollwood Drive Unit Keowee Interior, Seneca

The Listings data contained on this website comes from various participants of The Multiple Listing Service of Greenville, SC, Inc. Internet Data Exchange. IDX information is provided exclusively for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The properties displayed may not be all the properties available. All information provided is deemed reliable but is not guaranteed. © 2026 Greater Greenville Association of REALTORS®. All Rights Reserved. Last Updated